WPCD 2BVP ZCourier 10cpi?xxx,x6X@8;X@HP DeskJet 550CHPDES550.PRSx  @x,,0IX@#|x2B Wound Repair and Regeneration - Subject Index

Wound Repair and Regeneration

Cumulative Five Year Index

Subject Index

A

Abstracts

Abstracts from the First Joint Meeting of The Wound Healing Society and the European Tissue Repair Society. 1993;1:84-134

Abstracts from the Fourth Annual Meeting of The Wound Healing Society. 1994;2:64-99

Abstracts from the Fourth Annual Meeting of the European Tissue Repair Society. 1994;2:194-231

Abstracts from the Fifth Annual Meeting of The Wound Healing Society. 1995;3:76-108

Abstracts from the Fifth Annual meeting of the European Tissue Repair Society. 1995; 3:361-401

Abstracts from the 1995 Regeneration Forum. 1995;3:109-15

Abstracts from the Second Joint Meeting of The Wound Healing Society, The European Tissue Repair Society, The Japanese Society for Wound Healing, The Australian Wound Management Association and The Chinese Wound Healing Society. 1996;4:66-120

Abstracts from the Seventh Annual Meeting of The Wound Healing Society. 1997;5:A98-A129

Abstracts from the Seventh Annual Meeting of the European Tissue Repair Society. 1997;5:3:A255-95

Acidic fibroblast growth factor; see Fibroblast growth factor, acidic

Actins

Detection of the actin scavenger system in burn wound fluid (Grinnell et al). 1993;1:236-43

Actin fiber orientation in connective tissue contraction: a quantitative study with the perforated rat mesentery model (Franzén et al). 1996;4:454-60

Modulation of alpha-smooth muscle actin expression in fibroblasts by transforming growth factor-ß isoforms: an in vivo and in vitro study (Serini and Gabbiani). 1996;4:278-87

Adhensions

Role of fibrinolysis in the formation of postoperative adhesions (Holmdahl et al). 1994;2:171-6

Prevention of postoperative adhesions with the chitin derivative N-O carboxymethylchitosan (Krause et al). 1996;4:53-7

Adhesion molecule expression

In vitro analysis of adhesion molecule expression and gel contraction of human granulation fibroblasts (see Petri et al). 1997;5:69-76

Administration, topical

h)0*0*0*Ԍ

Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-L-histidyl-L-lysine copper (Mulder et al). 1994;2:259-69

Safety and effect of topical recombinant human interleukin-1&szling; in the management of pressure sores (Robson et al). 1994;2:177-81

Regulatory concerns in the development of topical recombinant ophthalmic and cutaneous wound healing biologics (Stromberg et al). 1994;2:155-64

Aged

Effect of growth hormone replacement on wound healing in healthy older men (Papadakis et al). 1996;4:421-5

Pressure ulcers in older persons: a preventive approach (Conlin Shaw). 1996;4:316-20

Differential expression of platelet-derived growth factor receptor-ß in an aging model of wound repair (Brucker et al). 1996;4:219-23

Skin changes with aging and disease (Jacobson and Flowers). 1996;4:311-5 (Perspective)

Aging

Acceleration of wound healing in aged rats by topical application of transforming growth factor-ß1 (Puolakkainen et al). 1995;3:330-9

Combination of platelet-derived growth factor-BB and insulin-like growth factor-I is more effective than platelet-derived growth factor-BB alone in stimulating complete healing of full-thickness wounds in "older" diabetic mice (Kiritsy et al). 1995;3:340-50

Aminoterminal propeptide

Influence of human growth hormone on granulation tissue formation, collagen deposition, and the aminoterminal propeptide of collagen type III in wound chambers in rats (Rasmussen et al). 1994;2:31-6

Amniotic fluid

In vitro and in vivo analysis of the inability of fetal rabbit wounds to contract (Krummel et al). 1993;1:15-21

Exposure to amniotic fluid inhibits closure of open wounds in the fetal rabit (Haynes et al). 1995;3:467-72

Amputation

Bone regrowth after digit tip amputation in mice is equivalent in adults and neonates (Neufeld and Zhao). 1995;3:461-6

Ananain

Removal of necrotic tissue with an ananain-based enzyme debriding preparation (Skrabut et al). 1996;4:433-43

Anastomosis, surgical

Pancreatic islet transplantation prevents the impaired healing of intestinal anastomoses in Lewis rats with streptozotocin-inducedh)0*0*0* diabetes (Verhofstad et al). 1995;3:221-8

Anemia, sickle cell

Histochemical analysis of growth factor, fibronectin, and iron content of sickle cell leg ulcers (Francillon et al). 1996;4:240-3

Anesthesia

Mild hypothermia during halothane-induced anesthesia decreases resistance to Staphylococcus aureus dermal infection in guinea pigs (Sheffield et al). 1994;2:48-56

Angiogenesis

Fibroblast growth factor-2 alters the effect of eroding polylactide-polyglycolide on angiogenesis in the bone chamber (Winet and Bao). 1997;5:355-63

Angiogenesis; see Neovascularization

Angiotensin II

Alterations of angiotensin II receptor levels in full-thickness excisional wounds in rat skin (Abiko et al). 1996;4:363-7

Acceleration of dermal tissue repair by angiotensin II (Rodgers et al). 1997;5:175-183

Anoxia

Role of hypoxia in growth factor responses: differential effects of basic fibroblast growth factor and platelet-derived growth factor in an ischemic wound model (Mustoe et al). 1994;2:277-83

Differential effects of oxygen on human dermal fibroblasts: acute versus chronic hypoxia (Siddiqui et al). 1996;4:211-8

Antibiotics

Development of a new wound dressing with antimicrobial delivery capability (Kuroyanagi et al). 1994;2:122-9

Antibodies

Effects of cytokines in burn blister fluids on fibroblast proliferation and their inhibition with the use of neutralizing antibodies (Inoue et al). 1996;4:426-32

Antigens

Correlation of transforming growth factor-alpha and epidermal growth factor receptor with proliferating cell nuclear antigen in human burn wounds (Wenczak and Nanney). 1993;1:219-30

Expression of proliferating cell nuclear antigen in cultured middle ear epithelial cells of the guinea pig (Takeno et al). 1996;4:115-20 (Symposium)

Antioxidant

In vitro studies on the antioxidant and growth stimulatory activities of a polyphenolic extract from cudrania cochinchinensis used in the treatment of wounds in Vietnamh)0*0*0*Ԍ(e Van Hien et al). 1997;5:159-67

Apoptosis

Covering by a flap induces apoptosis of granulation tissue myofibroblasts and vascular cells (Garbin et al). 1996;4:244-51

Aprotinin

Mechanical analysis of the effects of bacteria and aprotinin on skin wound healing in adult guinea pigs (Stadelmann et al). 1993;1:187-93

Athymic mice

Effective management of microbial contamination in cultured skin substitutes after grafting to athymic mice (Boyce et al). 1997;5:191-97

Epidermal lipid metabolism of cultured skin substitutes during healing of full-thickness wounds in athymic mice (Vi_anová et al). 1997;5:329-38

Autoradiography

Cellular distribution of epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor in fascia and peritoneum during healing in the rat: an autoradiographic and immunohistochemical study (Chegini et al).1993;1:2840

B

Bacteria

Mechanical analysis of the effects of bacteria and aprotinin on skin wound healing in adult guinea pigs (Stadelmann et al). 1993;1:187-93

Bandages

Analysis of therapy-resistant venous leg ulcers: Can triple-layer treatment initiate healing? (Bjellerup et al). 1993;1:54-62

Prospective randomized study of the efficacy of hydrogel, hydrocolloid, and saline solution-moistened dressings on the management of pressure ulcers (Mulder et al). 1993;1:213-8

Development of a new wound dressing with antimicrobial delivery capability (Kuroyanagi et al). 1994;2:122-9

Effect of oxygen treatment and dressing oxygen permeability on wound healing (Pandit and Feldman). 1994;2:130-7

Basic fibroblast growth factor see Fibroblast growth factor, basic

Biochemistry

Biochemical analysis of acute and chronic wound environments (Tarnuzzer and Schultz). 1996;4:321-5 (Perspective)

Biochemical analysis of wound fluid from nonhealing and healing chronic leg ulcers (Trengove et al). 1996;4:234-9

Biomechanics

Role of transforming growth factor-ß1 and epidermal growth factor in the wound-healing process: an in vivoh)0*0*0* biomechanical evaluation (Perry et al). 1993;1:41-6

Growth hormone increases the biomechanical strength and collagen deposition rate during the early phase of skin wound healing (Jørgensen and Oxlund). 1996;4:40-7

Blister

Effects of cytokines in burn blister fluids on fibroblast proliferation and their inhibition with the use of neutralizing antibodies (Inoue et al). 1996;4:426-32

Blood

Exchange and the mechanical properties of the skin: oncotic and hydrostatic forces control by blood supply and lymphatic drainage (Ryan). 1995;3:258-64 (Clinical issues)

Blood gas monitoring, transcutaneous

Centrally and locally mediated thermoregulatory responses alter subcutaneous oxygen tension (Sheffield et al). 1996;4:339-45

Transcutaneous oxygen measurements predict healing of leg wounds with hyperbaric therapy (Smith et al). 1996;4:224-9

Blood vessels, cytology

Covering by a flap induces apoptosis of granulation tissue myofibroblasts and vascular cells (Garbin et al). 1996;4:244-51

Body temperature regulation

Centrally and locally mediated thermoregulatory responses alter subcutaneous oxygen tension (Sheffield et al). 1996;4:339-45

Bone

Role of platelet-derived growth factor in osteoblast function and bone synthesis: conflicting evidence (Goodkin and Pierce). 1993;1:203-12

The combination of platelet-derived growth factor-BB and insulin-like growth factor-I stimulates bone repair in adult Yucatan miniature pigs (Lynch et al). 1994;2:182-90

Bone regrowth after digit tip amputation in mice is equivalent in adults and neonates (Neufeld and Zhao). 1995;3:461-6

Negatively charged beads and transforming growth factor-ß1 stim ulate bone repair in rabbits (Lyle et al). 1996;4:368-73

Bone chamber

Fibroblast growth factor-2 alters the effect of eroding polylactide-polyglycolide on angio-genesis in the bone chamber (Winet and Bao). 1997;5:355-63

Bone morphogenetic proteins

Expression of bone morphogenetic protein-4 mRNA during the process of bone formation in embryogenesis and fracture repair (Nakase et al). 1996;4:82-6 (Symposium)

Recombinant human bone morphogenetic proteins-2 and -4 induce several mesenchymal phenotypes in culture (Dixon et al). 1996;4:374-80

h)0*0*0*Ԍ

Burns

Effect of burn injury on corticosteroid-binding globulin levels in plasma and wound fluid (Garrel et al). 1993;1:10-4

Detection of the actin scavenger system in burn wound fluid (Grinnell et al). 1993;1:236-43

Correlation of transforming growth factor-alpha and epidermal growth factor receptor with proliferating cell nuclear antigen in human burn wounds (Wenczak and Nanney). 1993;1:219-30

Effects of basic fibroblast growth factor on the healing of partial thickness donor sites: a prospective, randomized, double-blind trial (Greenhalgh et al). 1994;2:113-21;

Effect of vibriolysin, an enzymatic debriding agent, on healing of partial-thickness burn wounds (Nanney et al); (Greenhalgh - Editorial comment) 1995;3:442-8, 540-1

Effects of cytokines in burn blister fluids on fibroblast proliferation and their inhibition with the use of neutralizing antibodies (Inoue et al). 1996;4:426-32

Expression of endogenous transforming growth factor-ß and its type I and type II receptors in rat burn wounds (see Wei et al). 1997;5:229-34<

Proteolytic activity in human burn wounds (Neely et al). 1997;5:302-09

C

Capillaries

Capillary morphogenesis during healing of full-thickness skin grafts; an ultrastructural study (Goretsky et al). 1995;3:213-20

Case reports

A late defect in wound healing associated with recurrent spontaneous pneumothoraces: a presumptive role for abnormal collagenase activity (Lindblad et al). 1995;3:15-24

Cell division

Inhibition of cell proliferation by chronic wound fluid (Bucalo et al). 1993;1:181-6

Effect of epidermal growth factor on cell proliferation in normal and wounded connective tissue (Malcherek et al). 1993;1:63-8

>

Suppression of in vitro proliferative scar fibroblast contraction by interferon alfa-2b (Sahara et al). 1993;1:22-7

Correlation of transforming growth factor-alpha and epidermal growth factor receptor with proliferating cell nuclear antigen in human burn wounds (Wenczak and Nanney). 1993;1:219-30

Cell engineering

Strategies for cell engineering in tissue repair (Brown et al). 1997;5:212-21

Cells, cultured

In vitro reconstituted skin as a tool for biology, pharmacology and therapy: a review (Eckes et al). 1995;3:248-57 (Perspective)

Cells, growth and development Progression of cellularh)0*0*0* repopulation and collagen synthesis in fresh-frozen allograft tendons (Nakamura et al). 1996;4:87-92 (Symposium)

Chemokine

Chemokine and inflammatory cytokine changes during chronic wound healing (Fivenson et al). 1997;5:310-22

Chemotaxis

Transforming growth factor-ß enhances connective tissue repair in perforated rat mesentery but not peritoneal macrophage chemotaxis (Franzén and Schultz). 1993;1:149-55

China

Wound healing research in China (Fu). 1995;3:237-8 (Letter)

Chitosan

Analysis of the effects of chitosan on inflammation, angiogenesis, fibroplasia, and collagen deposition in polyvinyl alchohol sponge implants in rat wounds (Diegelmann et al). 1996; 4:48-52

Prevention of postoperative adhesions with the chitin derivative N-O carboxymethylchitosan (Krause et al). 1996;4:53-7

Chronic wound healing

The role of growth factors in the healing of chronic wounds. (Robson et al) 1997;5:12-17

Chemokine and inflammatory cytokine changes during chronic wound healing (Fivenson et al). 1997;5:310-22

Chronic wound fluid

Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors (Yager et al). 1997;5:23-32

Chronic venus ulcers; see Ulcers

Cicatrix

Suppression of in vitro proliferative scar fibroblast contraction by interferon alfa-2b (Sahara et al). 1993;1:22-7

Regulation of collagen synthesis and messenger RNA levels in normal and hypertrophic scar fibroblasts in vitro by interferon alfa-2b (Tredget et al). 1993;1:156-65

Scarless human fetal skin repair is intrinsic to the fetal fibroblast and occurs in the absence of an inflammatory response: in situ hybridization and immunohistochemical studies (Lin et al). 1994;2:297-305

Autocrine transforming growth factor-ß1 activity and glycosaminoglycan synthesis by human cutaneous scar fibroblasts (Messadi et al). 1994;2:284-91

Hypertrophic scar fibroblasts accelerate collagen gel contraction (Garner et al). 1995;3:185-91

The role of transforming growth factor-ß in the conversion from "scarless" healing to healing with scar formation (Houghton et al). 1995;3:229-36

h)0*0*0*Ԍ

Excessive scarring as a consequence of healing (Ladin et al). 1995;3:6-14 (Perspective)

Gene expression of tenascin is altered in normal scars and keloids (Sible et al). 1995;3:37-48

Inhibition of tissue transglutaminase and epsilon (gamma-glutamyl) lysine cross-linking in human hypertrophic scar (Dolynchuk). 1996;4:16-20

Regulation of wound healing from a connective tissue perspective (Ehrlich and Krummel). 1996;4:203-10 (Perspective)

Hyaluronic acid-dependent pericellular matrices in fetal fibroblasts: implication for scar-free wound repair (Moriarty et al). 1996;4:346-52

Wound contraction and scar synthesis during development of the amphibian Rana cates-beiana (Yannas et al). 1996;4:29-39

Classification

Definitions and guidelines for assessment of wounds and evaluation of healing (Lazarus et al). 1994;2:165-70

Clinical issues

Exchange and the mechanical properties of the skin: oncotic and hydrostatic forces control by blood supply and lymphatic drainage (Ryan). 1995;3:258-64

Experimental approaches to chronic wounds (Falanga et al). 1995;3:132-40

Collagen

Regulation of collagen synthesis and messenger RNA levels in normal and hypertrophic scar fibroblasts in vitro by interferon alfa-2b (Tredget et al). 1993;1:156-66

Antiinflammatory prednisone derivatives inhibit collagen synthesis and pro-alpha1(I) collagen promoter activity in rat skin fibroblasts (Cutroneo et al). 1994;2:292-6

Dermal regeneration in native non-cross-linked collagen sponges with different extracellular matrix molecules (de Vries et al). 1994;2:37-47

Influence of human growth hormone on granulation tissue formation, collagen deposition, and the aminoterminal propeptide of collagen type III in wound chambers in rats (Rasmussen et al). 1994;2:31-6

Hypertrophic scar fibroblasts accelerate collagen gel contraction (Garner et al). 1995;3:185-91

Differential regulation of collagen gene expression in granulation tissue and nonrepair connective tissues in vitamin C-deficient guinea pigs (Kipp et al). 1995;3:192-203

In vivo characterization of interleukin-4 as a potential wound healing agent (Kucukcelebi et al). 1995;3:49-58

Excessive scarring as a consequence of healing (Ladin et al). 1995;3:6-14 (Perspective)

Altered collagen metabolism and delayed healing in a novel model of ischemic wounds (Schwarz et al). 1995;3:204-12

Regulation of wound healing from a connective tissue perspective (Ehrlich and Krummel). 1996;5:203-10 (Perspective)

A simple method to assess the relative amount of collagenh)0*0*0* deposition in wounded fetal mouse limbs (Houghton et al). 1996;4:489-95

Growth hormone increases the biomechanical strength and collagen deposition rate during the early phase of skin wound healing (Jørgensen and Oxlund). 1996;4:40-7

Progression of cellular repopulation and collagen synthesis in fresh-frozen allograft tendons (Nakamura et al). 1996;4:87-92 (Symposium)

Mesenchymal-epithelial interactions regulate gene expression of type VII collagen and kalinin in keratinocytes and dermal-epidermal junction formation in a skin equivalent model (Sahuc et al). 1996;4:93-102 (Symposium)

Development of a multilayered in vitro model for studying events associated with wound healing (Stephens et al). 1996;4:393-401

Collagen gel

Rate of tendon gap closure in an in vitro collagen gel matrix (Dombi et al). 1997;5:62-8

Collagenase

Interferons gamma and alpha-2b differentially regulate the expression of collagenase and tissue inhibitor of metalloproteinase-1 messenger RNA in human hypertrophic and normal dermal fibroblasts (Ghahary et al). 1995;3:176-84

A late defect in wound healing associated with recurrent spontaneous pneumothoraces: a presumptive role for abnormal collagenase activity (Lindblad et al). 1995;3:15-24 (Case rep.)

Collagenolytic activity

In vitro analysis of fetal fibroblast collagenolytic activity (see Gould et al) 1997;5:151-8

Color image analysis

Assessing wound severity with color and infrared imaging of reactive hypepremia (Hansen et al). 1996;4:386-92

Connective tissue

Transforming growth factor-ß enhances connective tissue repair in perforated rat mesentery but not peritoneal macrophage chemotaxis (Franzn and Schultz). 1993;1:149-55

Exogenous transforming growth factor-ß2 enhances connective tissue formation in trans-forming growth factor-ß1-deficient, healing-impaired dermal wounds in mice (Ksander et al). 1993;1:137-48

Effect of epidermal growth factor on cell proliferation in normal and wounded connective tissue (Malcherek et al). 1993;1:63-8

Mechanisms of TGF-ß action in connective tissue repair of rat mesenteric wounds (Franzén et al). 1995;3:322-9

Differential regulation of collagen gene expression in granulation tissue and nonrepair connective tissues in vitamin C-deficient guinea pigs (Kipp et al). 1995;3:192-203

Differential response to transforming growth factors-ß1h) 0*0*0* and szlig;2: connective tissue deposition in animal models (Ogawa et al). 1995;3:485-91

Regulation of wound healing from a connective tissue perspective (Ehrlich and Krummel). 1996;4:203-10 (Perspective)

Actin fiber orientation in connective tissue contraction: a quantitative study with the perforated rat mesentery model (Franzén et al). 1996;4:454-60

Hereditary disorders of connective tissue. (Klett and Diegelmann) 1997;5:3-11 (Perspective)

Continence Nurses Society

The case for a continuing liaison between the Wound Healing Society and the Wound, Ostomy and Continence Nurses Society (Clark). 1997;5:2 (Editorial)

Copper

Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-L-histidyl-L-lysine copper (Mulder et al). 1994;2:259-69

Cornea

Effect of platelet-derived growth factor on rabbit corneal wound healing (Stern et al). 1995;3:59-65

Rabbit cornea assay of angiogenesis: methodology and evaluation (Phillips and Knighton). 1995;3:533-9 (Technical note)

Corticosteroid-binding globulin; see Transcortin

Cost effectiveness

Long-term results of aggressive management of diabetic foot ulcers suggest significant cost effectiveness (Cianci and Hunt). 1997;5:141-6

Cyclophosphamide

Staphylococcus aureus peptidoglycan ameliorates cyclophosphamide-induced impairment of wound healing (Imegwu et al). 1997;5:364-72

Cytokines

Macrophage colony-stimulating factor induces indirect angiogenesis in vivo (Phillips et al). 1993;1:3-9

Experimental approaches to chronic wounds (Falanga et al). 1995;3:132-40 (Clinical issues)

Interleukin-1alpha gene expression during wound healing (Robertson et al). 1995;3:473-84

Surgical glove powders differentially modulate macrophage and lymphocyte-derived cytokines and eicosanoids production in vitro (Tang et al). 1995;3:518-26

Effects of cytokines in burn blister fluids on fibroblast proliferation and their inhibition with the use of neutralizing antibodies (Inoue et al). 1996;4:426-32

Interactions of cytokines, growth factors and proteases in acute and chronic wounds (Mast and Schultz). 1996;4:411-20

h) 0*0*0*Ԍ

Biochemical analysis of acute and chronic wound environments (Tarnuzzzer and Schultz). 1996;4:321-5 (Perspective)

Chemokine and inflammatory cytokine changes during chronic wound healing (Fivenson et al). 1997;5:310-20

D

Data Collection

Quantative analysis of wound healing (Bardsley et al). 1995;3:426-41

Debridement see Wound debridement

Decubitus ulcer

Prospective randomized study of the efficacy of hydrogel, hydrocolloid, and saline solution-moistened dressings on the management of pressure ulcers (Mulder et al). 1993;1:213-8

Safety and effect of topical recombinant human interleukin-1ß in the management of pressure sores (Robson et al). 1994;2:177-81

Involvement of proteolytic enzymes--plasminogen activators and matrix metalloproteinases-in the pathophysiology of pressure ulcers (Rogers et al). 1995;3:273-83

Effect of electrical stimulation waveform on healing of ulcers in human being with spinal cord injury (Baker et al). 1996;4:21-8
Pressure ulcers in older persons: a preventive approach (Conlin Shaw). 1996;4:316-20 (Perspective)

Dermis; see Skin

Dexamethasone

Inhibition of wound closure by transforming growth factor-ß amd dexamethasone in a fetal mouse limb organ culture model (Ehrlich et al). 1996;4:482-8

Diabetes mellitus

Synergistic actions of platelet-derived growth factor and the insulin-like growth factors in vivo: enhancement of tissue repair in genetically diabetic mice (Greenhalgh et al). 1993;1:69-81

Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-L-histidyl-L-lysine copper (Mulder et al). 1994;2:259-69<

Combination of platelet-derived growth factor-BB and insulin-like growth factor-I is more effective than platelet-derived growth factor-BB alone in stimulating complete healing of full-thickness wounds in "older" diabetic mice (Kiritsy et al). 1995;3:340-50

Healing of full-thickness wounds treated with lyophilized cultured keratinocyte cell lysate in genetically diabetic mice (Roseeuw et al). 1995; 3:500-5

Assessment of full-thickness wounds in the genetically diabetic mouse for suitability as a wound healing model (Senter et al). 1995;3:351-8

Recurrence rate of diabetic neurotrophic foot ulcers healed using topical application of growth factors released from platelets (Steed et al). 1996;4:230-3

h) 0*0*0*Ԍ

Diabetic rats

Reversal of the wound healing deficit in diabetic rats by combined basic fibroblast growth factor and transforming growth factor-ß1 therapy (Davidson et al). 1997;5:77-88

Diabetes mellitus, experimental

Pancreatic islet transplantation prevents the impaired healing of intestinal anastomoses in Lewis rats with streptozotocin-induced diabetes (Verhofstad et al). 1995;3:221-8

Discussion article

Wound pharmacology: a report from the wound pharmacology forum (Arnold et al). 1996;4:121-5 (Discussion article)

Donor site

Effects of basic fibroblast growth factor on the healing of partial thickness donor sites: a prospective, randomized, double-blind trial (Greenhalgh et al). 1994;2:113-21

Dressings; see Bandages

E

Ear

The hairless mouse ear: an in vivo model for studying wound neovascularization (Baker et al). 1994;2:138-43

Expression of proliferating cell nuclear antigen in cultured middle ear epithelial cells of the guinea pig (Takeno et al). 1996;4:115-20 (Symposium)

Editorials

Editorials 1993;1:1-2, 53, 202

The past, present, and future of wound healing (Cherry). 1995;3:119

Editorials 1994;2:1, 103, 236

Tissue repair: Where do we stand? (Westerhof). 1994;2:153-4

Editorials 1995;3:1-2, 119, 247, 406-7

Editorials 1996;4:1-2, 309

A time to integrate the complete wound team; from bench to bedside and beyond (Robson). 1996;4:187-8

How confidential is your review? (Lindblad). 1996;4:409-10

Editorials 1997;5:135, 211

The case for a continuing liaison between the Wound Healing Society and the Wound,Ostomy and Continence Nurses Society (Clark). 1997;5:2

Balkanization, rationalization, and the state of the Journal (Lindblad). 1997;5:301

Eiconsanoids

Surgical glove powders differentially modulate macrophage and lymphocyte-derived cytokines and eicosanoids production in vitro (Tang et al). 1995;3:518-26

Elastase

h) 0*0*0*Ԍ

Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors (Yager et al). 1997;5:23-32

Elderly; see Aged

Electric stimulation

Effect of electrical stimulation waveform on healing of ulcers in human being with spinal cord injury (Baker et al). 1996;4:21-8

Embryo

A population of cells resident within embryonic and newborn rat skeletal muscle is capable of differentiating into multiple mesodermal phenotypes (Lucas et al). 1995;3:449-60

Expression of bone morphogenetic protein-4 mRNA during the process of bone formation in embryogenesis and fracture repair (Nakase et al). 1996;4:82-6 (Symposium)

Endothelium

Inhibition of cell proliferation by chronic wound fluid (Bucalo et al). 1993;1:181-6

Enzymes

Microanalyses of enzymes and metabolites in ischemia/reperfusion-induced partial-thickness skin wounds (Im et al). 1993;1:253-8

Effect of vibriolysin, an enzymatic debriding agent, on healing of partial-thickness burn wounds (Nanney et al); (Greenhalgh - Editorial comment) 1995;3:442-8, 540-1

Removal of necrotic tissue with an ananain-based enzyme debriding preparation (Skrabut et al). 1996;4:433-43

Epidermal growth factor

Cellular distribution of epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor in fascia and peritoneum during healing in the rat: an autoradiographic and immunohistochemical study (Chegini et al). 1993;1:28-40

Effect of epidermal growth factor on cell proliferation in normal and wounded connective tissue (Malcherek et al). 1993;1:63-8

Role of transforming growth factor-ß1 and epidermal growth factor in the wound-healing process: an in vivo biomechanical evaluation (Perry et al). 1993;1:41-6

Correlation of transforming growth factor-alpha and epidermal growth factor receptor with proliferating cell nuclear antigen in human burn wounds (Wenczak and Nanney). 1993;1:219-30

Epidermal growth factor promotes wound repair of human respiratory epithelium (Zahm et al). 1993;1:175-80

Epidermis

Effect of ultraviolet radiation-induced inflammation on epidermal wound healing (Kaiser et al). 1995;3:311-5

h) 0*0*0*Ԍ

Surface electrical capacitance as an index of epidermal barrier properties of composite skin substitutes and skin autografts (Goretsky et al). 1995;3:419-25

Epidermal lipid metabolism of cultured skin substitutes during healing of full-thickness wounds in athymic mice (Vi_anová et al). 1997;5:329-38

Epithelium

Dermal substitutes for full-thickness wounds in a one-stage grafting model (de Vries et al). 1993;1:244-52

Epidermal growth factor promotes wound repair of human respiratory epithelium (Zahm et al). 1993;1:175-80

Ketanserin accelerates wound epithelialization and neovascularization (Kim et al). 1995; 3:506-11

Mesenchymal-epithelial interactions regulate gene expression of type VII collagen and kalinin in keratinocytes and dermal-epidermal junction formation in a skin equivalent model (Sahuc et al). 1996;4:93-102 (Symposium)

Expression of proliferating cell nuclear antigen in cultured middle ear epithelial cells of the guinea pig (Takeno et al). 1996;4:115-20 (Symposium)

Excisional wounds

Comparisons of wound healing among excisional laser-created, and standard thermal burns in porcine wounds of equal depth (Schaffer et al). 1997;5:52-61

Extracellular matrix

Dermal regeneration in native non-cross-linked collagen sponges with different extracellular matrix molecules (de Vries et al). 1994;2:37-47

Specific effects of glycosaminoglycans in an analog of extracellular matrix that delays wound contraction and induces regeneration (Shafritz et al). 1994;2:270-6

Biochemical analysis of acute and chronic wound environments (Tarnuzzer and Schultz). 1996;4:321-5 (Perspective)

Effects of transforming growth factor-ß1 on extracellular matrix gene expression by human fibroblasts from a laryngeal stenotic lesion (Macauley et al). 1996;4:269-77

Extracellular matrix protein turnover during salamander limb regeneration (Tassava et al). 1996;4:75-81 (Symposium)

F

Fabry, Wilhelm

Back to the future for wound care? The influences of Padua on wound management in Renaissance Europe (Kirkpatrick et al). 1996;4:326-34 (Historical article)

Fascia

Cellular distribution of epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor in fascia and peritoneum during healing in the rat: an autoradiographic and immunohistochemical study (Chegini et al). 1993;1:28-40

h)0*0*0*Ԍ

Fetus

In vitro and in vivo analysis of the inability of fetal rabbit wounds to contract (Krummel et al). 1993;1:15-21

Scarless human fetal skin repair is intrinsic to the fetal fibroblast and occurs in the absence of an inflammatory response: in situ hybridization and immunohistochemical studies (Lin et al). 1994;2:297-305

Wound healing in the fetus: possible role for inflammatory macrophages and transforming growth factor-ß isoforms (Longaker et al). 1994;2:104-12

Exposure to aminiotic fluid inhibits closure of open wounds in the fetal rabbit (Haynes et al). 1995;3:467-72

Transforming growth factor-ß1 reduces expansion of open wounds in the fetal rabbit (Alaish et al). 1996;4:477-81

Inhibition of wound closure by transforming growth factor and dexamethasone in a fetal mouse limb organ culture model (Ehrlich et al). 1996;4;482-8

A simple method to assess the relative amount of collagen deposition in wounded fetal mouse limbs (Houghton et al). 1996;4:489-95

Hyaluronic acid-dependent pericellular matrices in fetal fibroblasts: implication for scar-free wound repair (Moriarty et al). 1996;4:346-52

Expression of bone morphogenetic protein-4 mRNA during the process of bone formation in embryogenesis and fracture repair (Nakase et al). 1996;4:82-6 (Symposium)

Fetal wound healing: an overview (Olutoye and Cohen). 1996;4:66-74 (Symposium)

Tissue restoration: approaches and prospects (Stocum). 1996;4:3-15 (Perspective)

Transition from fetal to adult repair occurring in mouse forelimbs maintained in organ culture (Chopra et al). 1997;5:47-51

In vitro analysis of fetal fibroblast collagenolytic activity (Gould et al) 1997;5:151-8

Ultrastructural analysis of fetal rabbit wounds (Mast et al). 1997;5:243-8

Fibrin

Experimental approaches to chronic wounds (Falanga et al). 1995;3:132-40 (Clinical issues)

Fibrinolysis

Role of fibrinolysis in the formation of postoperative adhesions (Holmdahl et al). 1994;2:171-6

Fibroblasts

Inhibition of cell proliferation by chronic wound fluid (Bucalo et al). 1993;1:181-6

Suppression of in vitro proliferative scar fibroblast contraction by interferon alfa-2b (Sahara et al). 1993;1:22-7

Regulation of collagen synthesis and messenger RNA levels in normal and hypertrophic scar fibroblasts in vitro by interferon alpha-2b (Tredget et al). 1993;1:156-65

h)0*0*0*Ԍ

Antiinflammatory prednisolone derivatives inhibit collagen synthesis and pro-alpha1(I) collagen promoter activity in rat skin fibroblasts (Cutroneo et al). 1994;2:292-6

Scarless human fetal skin repair is intrinsic to the fetal fibroblast and occurs in the absence of an inflammatory response: in situ hybridization and immunohistochemical studies (Lin et al). 1994;2:297-305

Autocrine transforming growth factor-ß1 activity and glycosaminoglycan synthesis by human cutaneous scar fibroblasts (Messadi et al). 1994;2:284-91

Hypertrophic scar fibroblasts accelerate collagen gel contraction (Garner et al). 1995;3:185-91

Interferons gamma and alpha-2b differentially regulate the expression of collagenase and tissue inhibitor of metalloproteinase-1 messenger RNA in human hypertrophic and normal dermal fibroblasts (Ghahary et al). 1995;3:176-84

In vivo characterization of interleukin-4 as a potential wound healing agent (Kucukcelebi et al). 1995;3:49-58

Hyaluronic acid degradation products induce neovascularization and fibroplasia in fetal rabbit wounds (Mast et al). 1995;3:66-72

Fibroblast heterogeneity in the healing wound (Sempowski et al). 1995;3:120-31 (Perspective)

Effect of platelet-derived growth factor on rabbit corneal wound healing (Stern et al). 1995;3:59-65

Differential expression of platelet-derived growth factor receptors in porcine fibroblasts cultured from skin and granulation tissue (Ågren et al). 1996;4:288-96

Transforming growth factor-ß1 reduces expansion of open wounds in the fetal rabbit (Alaish et al). 1996;4:477-81

Effects of cytokines in burn blister fluids on fibroblast proliferation and their inhibition with the use of neutralizing antibodies (Inoue et al). 1996;4:426-32

Effects of transforming growth factor-ß1 on extracellular matrix gene expression by human fibroblasts from a laryngeal stenotic lesion (Macauley et al). 1996;4:269-77

Hyaluronic acid-dependent pericellular matrices in fetal fibroblasts: implication for scarfree wound repair (Moriarty et al). 1996;4:346-52

Characteristics of growth, morphology, and contractility, and protein expression of fibroblasts derived from keloid (Sato et al). 1996;4:104-14 (Symposium)

Modulation of alpha-smooth muscle actin expression in fibroblasts by transforming growth factor isoforms: an in vivo and in vitro study (Serini and Gabbiani). 1996;4:278-87

Differential effects of oxygen on human dermal fibroblasts: acute versus chronic hypoxia (Siddiqui et al). 1996;4:211-8

Development of a multilayered in vitro model for studying events associated with wound healing (Stephens et al). 1996;4:393-401

Wound fluids from saline solution- and Staphylococcus aureus peptidoylycan-inoculated sponges induce expression of matrix metalloproteinase 13 messenger ribonucleic acid by cultured rat fibroblasts (Liu et al). 1997; 5:349-54

h)0*0*0*Ԍ

Fibroblasts, granulation; see Granulation fibroblasts

Fibroblast growth factor-2

Fibroblast growth factor-2 alters the effect of eroding polylactide-polyglycolide on angio-genesis in the bone chamber (Winet and Bao). 1997;5:352-60

Fibroblast growth factor, acidic

Acidic fibroblast growth factor reduces renal morphologic and functional indicators of injury caused by ischemia and reperfusion (Fu et al). 1996;4:297-303

Fibroblast growth factor, basic

Increased gene expression of scatter factor-hepatocyte growth factor and basic fibroblast growth factor in granulation tissue in the rat (Steenfos et al). 1993;1:231-5

Effects of basic fibroblast growth factor on the healing of partial thickness donor sites: a prospective, randomized, double-blind trial (Greenhalgh and Rieman). 1994;2:113-21

Role of hypoxia in growth factor responses: differential effects of basic fibroblast growth factor and platelet-derived growth factor in an ischemic wound model (Mustoe et al). 1994;2:277-83

Ischemia and reperfusion reduce the endogenous basis fibroblast growth factor in rat skeletal muscles: an immunohistochemical study (Fu et al). 1996;4:381-5

Reversal of the wound healing deficit in diabetic rats by combined basic fibroblast growth factor and transforming growth factor-ß1 therapy (Davidson et al). 1997;5:77-88

Dose-dependent hyperbaric oxygen stimulation of human fibroblast proliferation (Hehenberger et al). 1997;5:147-50

Fibronectin

Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b (Ghahary et al). 1993;1:166-74

Fibronectin gene expression differs in normal and abnormal human wound healing (Sible et al). 1994;2:3-19

Histochemical analysis of growth factor, fibronectin, and iron content of sickle cell leg ulcers (Francillon et al). 1996;4:240-3

Fibroplasia

Analysis of the effects of chitosan on inflammation, angiogenesis, fibroplasia, and collagen deposition in polyvinyl alcohol sponge implants in rat wounds (Diegelmann et al). 1996; 4:48-52

Fibrosis

Canine subglottic stenosis as a model for excessive fibrosis: a pilot histologic and immunohistochemical analysis (Charous et al). 1996;4:444-53

h)0*0*0*Ԍ

Abrogation of the fibrotic effect of transforming growth factor-ß in dermal wound healing (Parrelli et al). 1997;5:136-40 (Perspective)

Fingers

Bone regrowth after digit tip amputation in mice is equivalent in adults and neonates (Neufeld and Zhao). 1995;3:461-6

Flaps; see Surgical flaps

Foot

Recurrence rate of diabetic neurotrophic foot ulcers healed using topical application of growth factors released from platelets (Steed et al). 1996;4:230-3

Long-term results of aggressive management of diabetic foot ulcers suggests significant cost effectiveness (Cianci and Hunt). 1997;5:141-6

Fractures

Expression of bone morphogenetic protein-4 mRNA during the process of bone formation in embryogenesis and fracture repair (Makase et al). 1996;4:82-6 (Symposium)

Full-thickness wounds

Epidermal lipid metabolism of cultured skin substitutes during healing of full-thickness wounds in athymic mice (Vicanová et al). 1997;5:329-38

G

Gamma-glutamyl lysine

Inhibition of tissue transglutaminase and epsilon(gamma-glutamyl) lysine cross-linking in human hypertrophic scar (Dolynchuk). 1996;4:16-20

Gastrectomy

Expression of interleukin-6 and tumor necrosis factor in peritoneal mononuclear cells after gastrectomy (Fujita et al). 1995;3:168-75

Gel contraction

In vitro analysis of adhesion molecule expression and gel contraction of human granulation fibroblasts (Petri et al). 1997;5:69-76

Gene expression

Increased gene expression of scatter factor-hepatocyte growth factor and basic fibroblast growth factor in granulation tissue in the rat (Steenfos et al). 1993;1:231-5

Fibronectin gene expression differs in normal and abnormal human wound healing (Sible et al). 1994;2:3-19

Differential regulation of collagen gene expression in granulation tissue and nonrepair connective tissues in vitamin C-deficient guinea pigs (Kipp et al). 1995;3:192-203

Gene expression of tenascin is altered in normal scars and keloids (Sible et al). 1995;3:37-48

h)0*0*0*Ԍ

Interleukin-1alpha gene expression during wound healing (Robertson et al). 1995;3:473-84

Effects of transforming growth factor-&szling1 on extracellular matrix gene expression by human fibroblasts from a laryngeal stenotic lesion (Macauley et al). 1996;4:269-77

Mesenchymal-epithelial interactions regulate gene expression of type VII collagen and kalinin in keratinocytes and dermal-epidermal junction formation in a skin equivalent model (Sahuc etal). 1996;4:93-102 (Symposium)

Glottis

Canine subglottic stenosis as a model for excessive fibrosis: a pilot histologic and immunohistochemical analysis (Charous et al). 1996;4:444-53

Gloves, surgical

Surgical glove powders differentially modulate macrophage and lymphocyte-derived cytokines and eicosanoids production in vitro (Tang et al). 1995;3:518-26

Postsurgical intraperitoneal exposure to glove powders modulates inflammatory and immune-related cytokine production (Rong et al.) 1997;5:89-91

Glycosaminoglycans

Autocrine transforming growth factor-ß1 activity and glycosaminoglycan synthesis by human cutaneous scar fibroblasts (Messadi et al). 1994;2:284-91

Specific effects of glycosaminoglycans in an analog of extracellular matrix that delays wound contraction and induces regeneration (Shafritz et al). 1994;2:270-6

Glycyl-L-histidyl-L-lysine copper

Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-L-histidyl-L-lysine copper (Mulder et al). 1994;2:259-69

Glucocorticoid steroid

Single local instillation of nonviable staphylococcus aureus or its peptidoglycan ameliorates glucocorticoid-induced impaired wound healing (Chang et al). 1997;5:184-90

Grafts

Dermal substitutes for full-thickness wounds in a one-stage grafting model (de Vries et al). 1993;1:244-52

Graft survival

Capillary morphogenesis during healing of full-thickness skin grafts: an ultrastructural study (Goretsky et al). 1995;3:213-20

Granulation fibroblasts, human

In vitro analysis of adhesion molecule expression and gel contraction of human granulation fibroblasts (Petri et al). 1997;5:69-76

h)0*0*0*Ԍ

Granulation tissue

Increased gene expression of scatter factor-hepatocyte growth factor and basic fibroblast growth factor in granulation tissue in the rat (Steenfos et al). 1993;1:231-5

Influence of human growth hormone on granulation tissue formation, collagen deposition, and the aminoterminal propeptide of collagen type III in wound chambers in rats (Rasmussen et al). 1994;2:31-6

Differential regulation of collagen gene expression in granulation tissue and nonrepair connective-tissues in vitamin C-deficient guinea pigs (Kipp et al). 1995;3:192-203

Exchange and the mechanical properties of the skin: oncotic and hydrostatic forces control by blood supply and lymphatic drainage (Ryan). 1995;3:258-64 (Clinical issues)

Differential expression of platelet-derived growth factor receptors in porcine fibroblasts cultured from skin and granulation tissue (Ågren et al). 1996;4:288-96

Covering by a flap induces apoptosis of granulation tissue myofibroblasts and vascular cells (Garbin et al). 1996;4:244-51

Growth factors

Experimental approaches to chronic wounds (Falanga et al). 1995;3:132-40 (Clinical issues)

Role of hypoxia in growth factor responses: differential effects of basic fibroblast growth factor and platelet-derived growth factor in an ischemic wound model (Mustoe et al). 1994;2:277-83

Hyaluronan: A potential carrier for growth factors for the healing of ligamentous tissues (Berry et al). 1997;5:33-8

The role of growth factors in the healing of chronic wounds (Robson). 1997;5:12-7(Clinical perspective)

Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors (Yager et al). 1997;5:23-32

Growth hormone

Influence of human growth hormone on granulation tissue formation, collagen deposition, and the aminoterminal propeptide of collagen type III in wound chambers in rats (Rasmussen et al). 1994;2:31-6

Growth hormone increases the biomechanical strength and collagen deposition rate during the early phase of skin wound healing (Jørgensen and Oxlund). 1996;4:40-7

Effect of growth hormone replacement on wound healing in healthy older men (Papadakis et al). 1996;4:421-5

Growth hormone but not insulin-like growth factor-I improves wound strength in pigs (Robertson et al). 1997;5:167-74

Growth substances

Biochemical analysis of acute and chronic wound environments (Tarnuzzer and Schultz). 1996;4:321-5 (Perspective)

Effect of growth factors on the characteristics of cells associated with equine wound healing and sarcoid formationh)0*0*0* (Cochrane et al). 1996;4:58-65

Histochemical analysis of growth factor, fibronectin, and iron content of sickle cell leg ulcers (Francillon et al). 1996;4:240-3

Interactions of cytokines, growth factors and proteases in acute and chronic wounds (Mast and Schultz). 1996;4:411-20(Perspective)

Recurrence rate of diabetic neurotrop hic foot ulcers healed using topical application of growth factors released from platelets (Steed et al). 1996;4:230-3

H

Halothane

Mild hypothermia during halothane-induced anesthesia decreases resistance to Staphylococcus aureus dermal infection in guinea pigs (Sheffield et al). 1994;2:48-56

Helium-neon

Low-energy helium-neon laser irradiation and the tensile strength of incisional wounds in the rat (Broadley et al). 1995;3:512-7

Hepatocyte growth factor

Increased gene expression of scatter factor-hepatocyte growth factor and basic fibroblast growth factor in granulation tissue in the rat (Steenfos et al). 1993;1:231-5

Hereditary disorders

Hereditary disorders of connective tissue: A review (Klett et al). 1997;5:3-11(Perspective)

Heterogeneity

Hyaluronan, heterogeneity, and healing: the effects of ultrapure hyaluronan of defined molecular size on the repair of full-thickness pig skin wounds (Arnold et al). 1995;3: 299-310<

Fibroblast heterogeneity in the healing wound (Sempowski et al). 1995;3:120-31 (Perspective)

Historical article

Back to the future for wound care? The influences of Padua on wound management in Renaissance Europe (Kirkpatrick et al). 1996;4:326-34

Hyaluronan

Hyaluronan, heterogeneity, and healing: the effects of ultrapure hyaluronan of defined molecular size on the repair of full-thickness pig skin wounds (Arnold et al). 1995;3: 299-310

Hyaluronan: A potential carrier for growth factors for the healing of ligamentous tissues (Berry et al). 1997;5:33-8

Hyaluronic acid

Hyaluronic acid degradation products induce neovascularization and fibroplasia in fetal rabbit wounds (Mast et al). 1995;3:66-72

h)0*0*0*Ԍ

Hyaluronic acid-dependent pericellular matrices in fetal fibroblasts: implication for scar-free wound repair (Moriarty et al). 1996;4:346-52

Hydrocolloids

Analysis of therapy-resistant venous leg ulcers: Can triple-layer treatment initiate healing? (Bjellerup et al). 1993;1:54-62

Prospective randomized study of the efficacy of hydrogel, hydrocolloid, and saline solution-moistened dressings on the management of pressure ulcers (Mulder et al). 1993;1:213-8

Hydrogel

Prospective randomized study of the efficacy of hydrogel, hydrocolloid, and saline solution-moistened dressings on the management of pressure ulcers (Mulder et al). 1993;1:213-8

Hyperbaric oxygen

Transcutaneous oxygen measurements predict healing of leg wounds with hyperbaric therapy (Smith et al). 1996;4:224-9

Dose-dependent hyperbaric oxygen stimulation of human fibroblast proliferation (Hehenberger et al). 1997;5:147-50

Hyperemia

Assessing wound severity with color and infrared imaging of reactive hyperemia (Hansen et al). 1996;4:386-92

Hypertrophy

Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b (Ghahary et al). 1993;1:166-74

Regulation of collagen synthesis and messenger RNA levels in normal and hypertrophic scar fibroblasts in vitro by interferon alfa-2b (Tredget et al). 1993;1:156-65

Interferons gamma and alpha-2b differentially regulate the expression of collagenase and tissue inhibitor of metalloproteinase-1 messenger RNA in human hypertrophic and normal dermal fibrolasts (Gahary et al). 1995;3:176-84

Hypertrophic scar fibroblasts accelerate collagen gel contraction (Garner et al). 1995;3:185-91

Inhibition of tissue transglutaminase and epsilon(gamma-glutamyl) lysine cross-linking in human hypertrophic scar Dolynchuk). 1996;4:16-20

Hypothermia

Mild hypothermia during halothane-induced anesthesia decreases resistance to Staphylococcus aureus dermal infection in guinea pigs (Sheffield et al). 1994;2:48-56

Hypoxia; see Anoxia

I

Immune-related cytokine

Postsurgical intraperitoneal exposure to glove powdersh)0*0*0* modulates inflammatory and immune-related cytokine production (Rong et al). 1997;5:89-96

Immunohistochemistry

Cellular distribution of epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor in fascia and peritoneum during healing in the rat: an autoradiographic and immunohistochemical study (Chegini et al). 1993;1:28-40

Scarless human fetal skin repair is intrinsic to the fetal fibroblast and occurs in the absence of an inflammatory response: in situ hybridization and immunohistochemical studies (Lin et al). 1994;2:297-305

Canine subglottic stenosis as a model for excessive fibrosis: a pilot histologic and immunohistochemical analysis (Charous et al). 1996;4:444-53

Ischemia and reperfusion reduce the endogenous basic fibroblast growth factor in rat skeletal muscle: an immunohistochemical study (Fu et al). 1996;4:381-5

Impaired healing

Mouse models to study wound closure and topical treatment of infected wounds in healing-impaired and normal healing hosts (Holder et al). 1997;5:198-204

Single local instillation of nonviable staphylococcus aureus or its peptidoglycan ameilorates glucocorticoid-induced impaired wound healing (Chang et al). 1997;5:184-90

Implants, artifical

Comparison of polyvinyl alcohol sponge and expanded polytetrafluoroethylene subcutaneous implants as models to evaluate wound healing potential in human beings (Alaish et al). 1995;3:292-8

Examination of expanded polytetrafluoroethylene wound healing models (Wicke et al). 1995;3:284-91

The wound healing process in surgical patients evaluated by the expanded polytetrafluoroethylene and the polyvinyl alcohol sponge: a comparison with special reference to intrapatient variability (Jorgensen et al). 1995;3:527-32

Analysis of the effects of chitosan on inflammation, angiogenesis, fibroplasia, and collagen deposition in polyvinyl alcohol sponge implants in rat wounds (Diegelmann et al). 1996; 4:48-52

Infant, newborn

Interstitial fluids associated with wound repair support proliferation but not differentiation of neonatal rat myoblasts in vitro (Sicard and Nguyen). 1994;2:306-13

A population of cells resident within embryonic and newborn rat skeletal muscle is capable of differentiating into multiple mesodermal phenotypes (Lucas et al). 1995;3:449-60

Bone regrowth after digit tip amputation in mice is equivalent in adults and neonates Neufeld and Zhao). 1995;3:461-6

Infected wounds

h)0*0*0*Ԍ

Mild hypothermia during halothane-induced anesthesia decreases resistance to Staphylococcus aureus dermal infection in guinea pigs (Sheffield et al). 1994;2:48-56

Mouse models to study wound closure and topical treatment of infected wounds in healing-impaired and normal healing hosts (Holder et al). 1997;5:198-204

Inflammation

Wound healing in the transforming growth factor-ß1-deficient mouse (Brown et al).1995;3:25-36

Effect of ultraviolet radiation-induced inflammation on epidermal wound healing (Kaiser et al). 1995,3:311-5

Analysis of the effects of chitosan on inflammation, angiogenesis, fibroplasia, and collagen deposition in polyvinyl alcohol sponge implants in rat wounds (Diegelmann et al). 1996; 4:48-52

Inflammatory cytokine

Chemokine and inflammatory cytokine changes during chronic wound healing (Fivenson et al). 1997;5:310-22

Postsurgical intraperitoneal exposure to glove powders modulates inflammatory and immune-related cytokine production (Rong et al). 1997;5:89-91

Infrared imaging

Assessing wound severity with color and infrared imaging of reactive hyperemia (Hansen et al). 1996;4:386-92

Insulin-like growth factor

Synergistic actions of platelet-derived growth factor and the insulin-like growth factors in vivo: enhancement of tissue repair in genetically diabetic mice (Greenhalgh et al). 1993; 1:69-81

The combination of platelet-derived growth factor-BB and insulin-like growth factor-I stimulates bone repair in adult Yucatan miniature pigs (Lynch et al). 1994;2:182-90

Combination of platelet-derived growth factor-BB and insulin-like growth factor-I is more effective than platelet-derived growth factor-BB alone in stimulating complete healing of full-thickness wounds in "older" diabetic mice (Kiritsy et al). 1995;3:340-50

Effects of insulin-like growth factor-I and insulin-like growth factor binding protein-1 on wound healing in a dermal ulcer model (Zhao et al). 1995;3:316-21

Increased specific binding of insulin-like growth factor-I in healing cutaneous wounds (Hakim et al). 1995;3:492-9

Local induction of an insulin-like growth factor binding protein-3 degrading protease activity in the course of wound healing (Fournier et al). 1996;4:252-8

Growth hormone but not insulin-like growth factor-I improves wound strength in pigs (Robertson et al). 1997;5:168-74

Integration of wound team

A time to integrate the complete wound team; from bench to bedside and beyond (Robson). 1996;4:187-8 (Editorial)

h)0*0*0*Ԍ

Interferons

Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b (Ghahary et al). 1993;1:166-74

Suppression of in vitro proliferative scar fibroblast contraction by interferon alfa-2b (Sahara et al). 1993;1:22-7

Regulation of collagen synthesis and messenger RNA levels in normal and hypertrophic scar fibroblasts in vitro by interferon alfa-2b (Tredget et al). 1993;1:156-65

Interferons gamma and alpha-2b differentially regulate the expression of collagenase and tissue inhibitor of metalloproteinase-1 messenger RNA in human hypertrophic and normal dermal fibroblasts (Ghahary et al). 1995;3:176-84

Interleukins

Safety and effect of topical recombinant human interleukin-1ß in the management of pressure sores (Robson et al). 1994;2:177-81

Expression of interleukin-6 and tumor necrosis factor in peritoneal mononuclear cells after gastrectomy (Fujita et al). 1995;3:168-75

In vivo characterization of interleukin-4 as a potential wound healing agent (Kucukcelebi et al) 1995;3:49-58

Interleukin-1alpha gene expression during wound healing (Robertson et al). 1995;3:473-84

Interobserver agreement; see Observer variation

Interstitial fluid

Interstitial fluids associated with wound repair support proliferation but not differentiation of neonatal rat myoblasts in vitro (Sicard and Nguyen). 1994;2:306-13

Intestines

Pancreatic islet transplantation prevents the impaired healing of intestinal anastomoses in Lewis rats with streptozotocin-induced diabetes (Verhofstad et al). 1995;3:221-8

Intraperitoneal

Postsurgical intraperitoneal exposure to glove powders modulates inflammatory and immune-cytokine production (Rong et al). 1997;5:89-96

Iron

Histochemical analysis of growth factor, fibronectin, and iron content of sickle cell leg ulcers (Francillon et al). 1996;4:240-3

Ischemia

Microanalyses and metabolites in ischemia/reperfusion-induced partial-thickness skin wounds (Im et al). 1993;1:253-8

Role of hypoxia in growth factor responses: differential effects of basic fibroblast growth factor and platelet-derivedh)0*0*0* growth factor in an ischemic wound model (Mustoe et al). 1994;2:277-83

Altered collagen metabolism and delayed healing in a novel model of ischemic wounds (Schwarz et al). 1995;3:204-12

Acidic fibroblast growth factor reduces renal morphologic and functional indicators of injury caused by ischemia and reperfusion (Fu et al). 1996;4:297-303

Ischemia and reperfusion reduce the endogenous basic fibroblast growth factor in rat skeletal muscles: an immunohistochemical study (Fu et al). 1996;4:381-5

Islets of Langerhans transplantation

Pancreatic islet transplanation prevents the impaired healing of intestinal anastomoses in Lewis rats with streptozotocin-induced diabetes (Verhofstad et al). 1995;3:221-8

K

Kalinin

Mesenchymal-epithelial interactions regulate gene expression of type VII collagen and kalinin in keratinocytes and dermal-epidermal junction formation in a skin equivalent model (Sahuc et al). 1996;4:93-102 (Symposium)

Keloids

Excessive scarring as a consequence of healing (Ladin et al). 1995;3:6-14 (Perspective)

Gene expression of tenascin is altered in normal scars and keloids (Sible et al). 1995;3:37-48

Characteristics of growth, morphology, and contractility, and protein expression of fibroblasts derived from keloid (Sato et al). 1996;4:103-14 (Symposium)

Keratinocytes

Inhibition of cell proliferation by chronic wound fluid (Bucalo et al). 1993;1:181-6

Experimental approaches to chronic wounds (Falanga et al). 1995;3:132-40 (Clinical issues)

Healing of full-thickness wounds treated with lyophilized cultured keratinocyte cell lysate in genetically diabetic mice (Roseeuw et al). 1995;3:500-5

Mesenchymal-epithelial interactions regulate gene expression of type VII collagen and kalinin in keratinocytes and dermal-epidermal junction formation in a skin equivalent model (Sahuc et al) 1996;4:93-102 (Symposium)

Ketanserin

Ketanserin accelerates wound ephithelialization and neovascularization (Kim et al). 1995;3:506-11

Kidney

Acidic fibroblast growth factor reduces renal morphologic and functional indicators of injury caused by ischemia and referfusion (Fu et al). 1996;4:297-303

h)0*0*0*Ԍ

L

Lactates

Experimental approaches to chronic wounds (Falanga et al). 1995;3:132-40 (Clinical issues)

Laryngeal diseases

Effects of transforming growth factor-ß1 on extracellular matrix gene expression by human fibroblasts from a laryngeal stenotic lesion (Macauley et al). 1996;4:269-77

Laser-created wounds

Comparisons of wound healing among excisional, laser-created, and standard thermal burns in porcine wounds of equal depth (Schaffer et al). 1997;5:52-61

Laser therapy

Low-energy helium-neon laser irradiation and the tensile strength of incisional wounds in the rat (Broadley et al). 1995;3:512-7

Leg ulcer

Analysis of therapy-resistant venous leg ulcers: Can triple-layer treatment initiate healing? (Bjellerup et al). 1993;1:54-62

Histochemical analysis of growth factor, fibronectin, and iron content of sickle cell leg ulcers (Francillon et al). 1996;4:240-3

Transcutaneous oxygen measurements predict healing of leg wounds with hyperbaric therapy (Smith et al). 1996;4:224-9

Biochemical analysis of wound fluid from nonhealing and healing chronic leg ulcers (Trengove et al). 1996;4:234-9

Leukotriene receptors

Cellular distribution of 5-lipoxygenase and leukotriene receptors in postsurgical peritoneal wound repair (see Chegini et al). 1997;5:235-42

Lifetime Achievement Award

Wound healing: A personal odyssey (Levenson). 1994;2:238-58 (Award recipient address)

Reflections on wound healing and regeneration (Peacock). 1995;3:3-5 (Award recipient address)

Getting to mammalian wound repair and amphibian limb regeneration: a mechanistic link in the early events (Gross). 1996;4:190-202 (Award recipient address)

Ligamentous tissues

Hyaluronan: A potential carrier for growth factors for the healing of ligamentous tissues (Berry et al). 1997;5:33-8

Limb regeneration

Getting to mammalian wound repair and amphibian limb regeneration: a mechanistic link in the early events (Gross). 1996;4:190-202 (Award recipient address)

h)0*0*0*Ԍ

Extracellular matrix protein turnover during salamander limb regeneration (Tassava et al). 1996;4:75-81 (Symposium)

Lipid metabolism

Epidermal lipid metabolism of cultured skin substitutes during healing of full-thickness wounds in athymic mice (Vi_anová et al). 1997;5:3297-38

5-Lipoxygenase

Cellular distribution of 5-lipoxygenase and leukotriene receptors in postsurgical peritoneal wound repair (Chegini et al). 1997;5:235-42

Lymphatic system

Exchange and the mechanical properties of the skin: oncotic and hydrostatic forces control by blood supply and lymphatic drainage (Ryan). 1995;3:258-64 (Clinical issues)

Lymphocytes

Surgical glove powders differentially modulate macrophage and lymphocyte-derived cytokines and eicosanoids production in vitro (Tang et al). 1995;3:518-26

M

Macrophage colony-stimulating factor

Macrophage colony-stimulating factor induces indirect angiogenesis in vivo (Phillips et al). 1993;1:3-9

Macrophages

Transforming growth factor-ß enhances connective tissue repair in perforated rat mesentery but not peritoneal macrophage chemotaxis (Franzén and Schultz). 1993;1:149-55

Wound healing in the fetus: possible role for inflammatory macrophages and transforming growth factor-ß isoforms (Longaker et al). 1994;2:104-12

Surgical glove powders differentially modulate macrophage and lymphocyte-derived cytokines and eicosanoids production in vitro (Tang et al). 1995;3:518-26

Matrix metalloproteinase

Experimental approaches to chronic wounds (Falanga et al). 1995;3:132-40 (Clinical issues)

Interferons gamma and alpha-2b differentially regulate the expression of collagenase and tissue inhibitor of metalloproteinase-1 messenger RNA in human hypertrophic and normal dermal fibroblasts (Ghahary et al). 1995;3:176-84

Involvement of proteolytic enzymes--plasminogen activators and matrix metalloproteinases-- in the pathophysiology of pressure ulcers (Rogers et al). 1995;3:273-83

Wound fluids from saline solution- and staphylococcus aureus peptidoglycan-inoculated sponges induce expression of matrix metalloproteinase 13 messenger ribonucleic acid by cultured rate fibroblasts (Liu et al). 1997;5:349-54

h)0*0*0*Ԍ

Mesenchyma

Recombinant human bone morphogenetic proteins-2 and -4 induce several mesenchymal phenotypes in culture (Dixon et al). 1996;4:374-80

Mesenchymal-epithelial interactions regulate gene expression of type VII collagen and kalinin in keratinocytes and dermal-epidermal junction formation in a skin equivalent model (Sahuc et al). 1996;4:93-103 (Symposium)

Mesenteric wounds

Alpha-smooth muscle actin expression in rat and mouse mesenteric wounds after TGF-ß1 treatment (Ghassemifar et al). 1997;5:339-48

Mesentery<

Transforming growth factor-ß enhances connective tissue repair in perforated rat mesentery but not peritoneal macrophage chemotaxis (Franzén and Schultz). 1993;1:149-55

Mechanisms of TGF-ß action in connective tissue repair of rat mesenteric wounds (Franzén et al). 1995;3:322-9

Actin fiber orientation in connective tissue contraction: a quantitative study with the perforated rat mesentery model (Franzén et al). 1996;4:454-60

Mesoderm

A population of cells resident within embryonic and newborn rat skeletal muscle is capable of differentiating into multiple mesodermal phenotypes (Lucas et al). 1995;3:449-60

Messenger RNA; see RNA, messenger

Microbial contamination
Effective management of microbial contamination in cultured skin substitutes after grafting to athymic mice (Boyce et al). 1997;5:191-7

Middle ear; see Ear

Models

The hairless mouse ear: an in vivo model for studying wound neovascularization (Barker et al). 1994;2:138-43

Evaluation of the wound healing potential in human beings from the subcutaneous insertion of expanded polytetrafluoroethylene tubes: a methodologic study (Jorgensen et al). 1994;2:20-30

Comparison of polyvinyl alcohol sponge and expanded polytetrafluoroethylene subcutaneous implants as models to evaluate wound healing potential in human beings (Alaish et al). 1995;3:292-8

Quantitative analysis of wound healing (Bardsley et al). 1995;3:426-41

The wound healing process in surgical patients evaluated by the expanded polytetrafluoroethylene and the polyvinyl alcohol sponge: a comparison with special reference to intrapatient variability (Jorgensen et al). 1995;3:527-32

Differential response to transforming growth factors-ß1 and ß2: connective tissue deposition in animal models (Ogawah)0*0*0* et al). 1995;3:485-91

Transforming growth factor-ß: activity and efficacy in animal models of wound healing (Roberts). 1995;3:408-18 (Perspective)

Altered collagen metabolism and delayed healing in a novel model of ischemic wounds (Schwarz et al). 1995;3:204-12

Assessment of full-thickness wounds in the genetically diabetic mouse for suitability as a wound healing model (Senter et al). 1995;3:351-8

Examination of expanded polytetrafluoroethylene wound healing models (Wicke et al). 1995;3:284-91<

Effects of insulin-like growth factor-I on wound healing in a dermal ulcer model (Zhao et al). 1995;3:316-21

Differential expression of platelet-derived growth factor receptor-ß in an aging model of wound repair (Brucker et al). 1996;4:219-23

Canine subglottic stenosis as a model for excessive fibrosis: a pilot histologic and immunohistochemical analysis (Charous et al). 1996;4:444-53

Inhibition of wound closure by transforming growth factor-ß and dexamethasone in a fetal mouse limb organ culture model (Ehrlich et al). 1996;4:482-8

Actin fiber orientation in connective tissue contraction: a quantitative study with the perforated rat mesentery model (Franzén et al). 1996;4:454-60

Mesenchymal-epithelial interactions regulate geneketinocytes and dermal-epidermal junction formation in a skin equivalent model (Sahuc et al). 1996;4:93-102 (Symposium)

Development of a multilayered in vitro model for studying events associated with wound healing (Stephens et al). 1996;4:393-401

Mouse models to study wound closure and topical treatment of infected wounds in healing-impaired and normal healing hosts (see Holder et al). 1997;5:198-204

Morphogenesis

Recombinant human bone morphogenetic proteins-2 and -4 induce several mesenchymal phenotypes in culture (Dixon et al). 1996;4:374-80

Expression of bone morphogenetic protein-4 mRNA during the process of bone formation in embryogenesis and fracture repair (Nakase et al). 1996;4:82-6 (Symposium)

Mouse forelimbs

Transition from fetal to adult repair occurring in mouse forelimbs maintained in organ culture (Chopra et al). 1997;5:47-51

mRNA; see RNA,messenger

Muscle

A population of cells resident within embryonic and newborn rat skeletal muscle is capable of differentiating into multiple mesodermal phenotypes (Lucas et al). 1995;3:449-60

Ischemia and reperfusion reduce the endogenous basic fibroblasth)0*0*0* growth factor in rat skeletal muscles: an immunohistochemical study (Fu et al). 1996;4:381-5

Mammalian wound repair environment does not permit skeletal muscle regeneration (Sicard et al).1997;5:39-46

Muscle, smooth

Modulation of alpha-smooth muscle actin expression in fibroblasts by transforming growth factor-isoforms: an in vivo and in vitro study (Serini and Gabbiani). 1996;4:278-87

Myoblasts

Interstitial fluids associated with wound repair support proliferation but not differentiation of neonatal rat myoblasts in vitro (Sicard and Nguyen). 1994;2:306-13

Myofibroblasts

Covering by a flap induces apoptosis of granulation tissue myofibroblasts and vascular cells (Garbin et al). 1996;4:244-51

N

Nasal mucosa

Epidermal growth factor promotes wound repair of human respiratory epithelium (Zahm et al). 1993;1:175-80

Necrosis

Removal of necrotic tissue with an ananain-based enzyme debriding preparation (Skrabut et al). 1996;4:433-43

Negatively charged beads

Negatively charged beads and transforming growth factor-ß1 stimulate bone repair in rabbits (Lyle et al). 1964:368-73

Neonate; see Infant, newborn

Neovascularization

Macrophage colony-stimulating factor induces indirect angiogenesis in vivo (Phillips et al). 1993;1:3-9

The hairless mouse ear: an in vivo model for studying wound neovascularization (Barker et al). 1994;2:138-43

Ketanserin accelerates wound epithelialization and neovascularization (Kim et al). 1995;3:506-11

Hyaluronic acid degradation products induce neovascularization and fibroplasia in fetal rabbit wounds (Mast et al). 1995;3:66-72

Rabbit cornea assay of angiogenesis: methodology and evaluation (Phillips and Knighton). 1995;3:533-9 (Technical note)

Analysis of the effects of chitosan on inflammation, angiogenesis, fibroplasia, and collagen deposition in polyvinyl alcohol sponge implants in rat wounds (Diegelmann et al). 1996; 4:48-52

Neutralizing antibodies; see Antibodies

Neutrophils

Macrophage colony-stimulating factor induces indirecth)0*0*0* angiogenesis in vivo (Phillips et al). 1993;1:3-9

Newborn; see Infant, newborn

Nitric oxide

Enhancement of wound repair with a topically applied nitric oxide-releasing polymer (Shabani et al). 1996;4:353-62

N-O-carboxymethylchitosan; see Chitosan

Nuclear antigens; see Antigens

O

Observer variation

Interobserver agreement, sensitivity, and specificiy of a "healed" chronic wound (Margolis et al). 1996;4:335-8

Organ culture

Transition from fetal to adult repair occurring in mouse forelimbs maintained in organ culture (Chopra et al). 1997;5:47-51

Ophthalmic preparations

Regulatory concerns in the development of topical recombinant ophthalmic and cutaneous wound healing biologics (Stromberg et al). 1994;2:155-64

Osteoblasts

Role of platelet-derived growth factor in osteoblast function and bone synthesis: conflicting evidence (Goodkin and Pierce). 1993;1:203-12

Oxygen

Effect of oxygen treatment and dressing oxygen permeability on wound healing (Pandit and Feldman). 1994;2:130-7

Centrally and locally mediated thermoregulatory responses alter subcutaneous oxygen tension (Sheffield et al). 1996;4:339-45

Differential effects of oxygen on human dermal fibroblasts: acute versus chronic hypoxia (Siddiqui et al). 1996;4:211-8

Transcutaneous oxygen measurements predict healing of leg wounds with hyperbaric therapy (Smith et al). 1996;4:224-9

P

Padua, medical school of

Back to the future for wound care? The influences of Padua on wound management in Renaissance Europe (Kirkpatrick et al). 1996;4:326-34 (Historical article)

Pancreatic islet transplantation; see Islets of Langerhans transplantation

Peptide Growth factors

Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors. (Yager et al). 1997;5:23-32

h) 0*0*0*Ԍ

Peptidoglycan

Wound healing I: accelerating effects of nonviable Staphylococcus aureus; its cell wall peptidoglycan (Levenson et al). 1996;4:461-9

Molecular mechanisms underlying wound healing acceleration by Staphylococcus aureus peptidoglycan (Liu et al). 1996;4:470-6

Single local instillation of nonviable Staphylococcus aureus or its peptidoglycan ameliorates glucocorticoid-induced impaired wound healing (Chang et al). 1997;5:184-90

Staphylococcus aureus peptidoglycan ameliorates cyclophosphamide-induced impairment of wound healing (Imegwu et al). 1997;5:364-72

Wound fluids from saline solution- and Staphylococcus aureus peptidoglycan-inoculated sponges induce expression of matrix metalloproteinase 13 messenger ribonucleic acid by cultured rat fibroblasts (Liu et al). 1997;5:349-54

Peritoneal wounds

Cellular distribution of 5-lipoxygenase and leukotriene receptors in postsurgical peritoneal wound repair (Chegini et al). 1997;5:235-42

Peritoneum

Cellular distribution of epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor in fascia and peritoneum during healing in the rat: an autoradiographic and immunohistochemical study (Chegini et al). 1993;1:28-40

Transforming growth factor-ß enhances connective tissue repair in perforated rat mesentery but not peritoneal macrophage chemotaxis (Franzn and Schultz). 1993;1:149-55

Expression of interleukin-6 and tumor necrosis factor in peritoneal mononuclear cells after gastrectomy (Fujita et al). 1995;3:268-75

Perspective articles

Role of platelet-derived growth factor in osteoblast function and bone synthesis (Goodkin and Pierce) 1993;1:203-12

In vitro reconstituted skin as a tool for biology, pharmacology and therapy: a review (Eckes et al). 1995;3:248-57

Excessive scarring as a consequence of healing (Ladin et al). 1995;3:6-14

Transforming growth factor-ß: activity and efficacy in animal models of wound healing (Roberts). 1995;3:408-18

Fibroblast heterogeneity in the healing wound (Sempowski et al). 1995;3:120-31

Pressure ulcers in older persons: a preventive approach (Conlin Shaw). 1996;4:316-20

Regulation of wound healing from a connective tissue perspective (Ehrlich and Krummel). 1996;4:203-10

Skin changes with aging and disease (Jacobson and Flowers). 1996;4:311-5

Tissue restoration: approaches and prospects (Stocum).h)!0*0*0* 1996;4:3-15

Biochemical analysis of acute and chronic wound environments (Tarnuzzer and Schultz). 1996;4:321-5

Strategies for cell engineering in tissue repair (Brown et al). 1997;5:212-21

>DD>Hereditary disorders of connective tissue: A review (Klett and Diegelmann). 1997;5:3-11

Abrogation of the fibrotic effect of transforming growth factor-ß in dermal wound healing (Parrelli et al). 1997;5:136-40

Pharmacology

In vitro reconstituted skin as a tool for biology, pharmacology and therapy: a review (Eckes et al). 1995;3:248-57 (Perspective)

Wound pharmacology: a report from the wound pharmacology forum (Arnold et al). 1996;4:121-5 (Discussion article)

Plasma

Effect of burn injury on corticosteroid-binding globulin levels in plasma and wound fluid (Garrel et al). 1993;1:10-4

Plasminogen activators

Involvement of proteolytic enzymes--plasminogen activators and matrix metalloproteinases-- in the pathophysiology of pressure ulcers (Rogers et al). 1995;3:273-83

Platelet-derived growth factor

Role of platelet-derived growth factor in osteoblast function and bone synthesis (Goodkin and Pierce) 1993;1:203-12

Synergistic actions of platelet-derived growth factor and the insulin-like growth factors in vivo: enhancement of tissue repair in genetically diabetic mice (Greenhalgh et al). 1993;1:69-81

The combination of platelet-derived growth factor-BB and insulin-like growth factor-I stimulates bone repair in adult Yucatan miniature pigs (Lynch et al). 1994;2:182-90

Role of hypoxia in growth factor responses: differential effects of basic fibroblast growth factor and platelet derived growth factor in an ischemic wound model (Mustoe et al). 1994;2:277-83

Combination of platelet-derived growth factor-BB and insulin-like growth factor-I is more effective than platelet-derived growth factor-BB alone in stimulating complete healing of full-thickness wounds in "older" diabetic mice (Kiritsy et al). 1995;3:340-50

Localization of platelet-derived growth factor receptor subunit expression in chronic venous leg ulcers (Peus et al). 1995;3:265-72

Effect of platelet-derived growth factor on rabbit corneal wound healing (Stern et al). 1995;3:59-65

Differential expression of platelet-derived growth factor receptors in porcine fibroblasts cultured from skin and granulation tissue (Ågren et al). 1996;4:288-96

Differential expression of platelet-derived growth factor receptor-( in an aging model of wound repair (Brucker et al).h)"0*0*0* 1996;4:219-23

Pneumothorax

A late defect in wound healing associated with recurrent spontaneous pneumothoraces: a presumptive role for abnormal collagenase activity (Lindblad et al). 1995;3:15-24 (Case rep.)

Polyethyleneimine cellulose NONOate polymer

Enhancement of wound repair with a topically applied nitric oxide-releasing polymer (Shabani et al). 1996;4:353-62

Polylactide-polyglycolide

Fibroblast growth factor-2 alters the effect of eroding polylactide-polyglycolide on angio genesis in the bone chamber (Winet and Bao). 1997;5:355-63

Polyphenolic extract

In vitro studies on the antioxidant and growth stimulatory activities of a polyphenolic extract from cudrania cochinchinensis used in the treatment of wounds in Vietnam (Van Hien et al). 1997;5:159-67

Polytetrafluoroethylene

Evaluation of the wound healing potential in human beings from the subcutaneous insertion of expanded polytetrafluoroethylene tubes: a methodologic study (Jorgensen et al). 1994;2:20-30

Comparison of polyvinyl alcohol sponge and expanded polytetrafluoroethylene subcutaneous implants as models to evaluate wound healing potential in human beings (Alaish et al). 1995;3:292-8

The wound healing process in surgical patients evaluated by the expanded polytetrafluoro ethylene and the polyvinyl alcohol sponge: a comparison with special reference to intrapatient variability (Jorgensen et al). 1995;3:527-32

Examination of expanded polytetrafluoroethylene wound healing models (Wicke et al). 1995;3:284-91

Polyvinyl alcohol sponge

Comparison of polyvinyl alcohol sponge and expanded polytetrafluoroethylene subcutaneous implants as models to evaluate wound healing potential in human beings (Alaish et al). 1995;3:292-8

The wound healing process in surgical patients evaluated by the expanded polytetrafluoro ethylene and the polyvinyl alcohol sponge: a comparison with special reference to intrapatient variability (Jorgensen et al). 1995;3:527-32

Polyvinyl alcohol sponge implants; see Implants, artifical

Porcine wounds

Growth hormone but not insulin-like growth factor-I improves wound strength in pigs (Robertson et al). 1997;5:168-74

Comparisons of wound healing among excisional, laser-created,h)#0*0*0* and standard thermal burns in porcine wounds of equal depth (Schaffer et al) 1997;5:52-61

Prednisolone

Antiinflammatory prednisolone derivatives inhibit collagen synthesis and pro-alpha1(I) collagen promoter activity in rat skin fibroblasts (Cutroneo et al). 1994;2:292-6

Pregnancy

Wound healing in the fetus: possible role for inflammatory macrophages and transforming growth factor-ß isoforms (Longaker et al). 1994;2:104-12

Exposure to amniotic fluid inhibits closure of open wounds in the fetal rabbit (Haynes et al). 1995;3:467-72

Pressure ulcer; see Decubitus ulcer

Progenitor cells; see Stem cells

Proliferating cell nuclear antigens; see Antigens

Proliferation, cellular; see Cell division

Proteinase inhibitors

Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors (Yager et al). 1997;5:23-32

Proteolytic activity

Proteolytic activity in human burn wounds (Neely et al). 1997;5:302-9

Proteolytic enzymes

Involvement of proteolytic enzymes-plasminogen activators and matrix metalloproteinases--in the pathophysiology of pressure ulcers (Rogers et al). 1995;3:273-83

Proteases

Local induction of an insulin-like growth factor binding protein-3 degrading protease activity in the course of wound healing (Fournier et al). 1996;4:252-8

Interactions of cytokines, growth factors and proteases in acute and chronic wounds (Mast and Schultz). 1996;4:411-20

Protein-glutamine gamma-glutamyltransferase

Inhibition of tissue transglutaminase and epsilon(gamma-glutamyl) lysine cross-linking in human hypertrophic scar (Dolynchuk). 1996;4:16-20

R

Rabbit wounds

Ultrastructural analysis of fetal rabbit wounds (Mast et al). 1997;5:243-8

Early tracheostomal healing in rabbits with use of various trachael incisions (Whitley et al). 1997;5:321-6

h)$0*0*0*Ԍ

Receptors, angiotensin

Alterations of angiotensin II receptor levels in full-thickness excisional wounds in rat skin (Abiko et al). 1996;4:363-7

Receptors, epidermal growth factor

Cellular distribution of epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor in fascia and peritoneum during healing in the rat: an autoradiographic and immunohistochemical study (Chegini et al). 1993;1:28-40

Correlation of transforming growth factor-alpha and epidermal growth factor receptor with proliferating cell nuclear antigen in human burn wounds (Wenczak and Nanney). 1993;1:219-30

Receptors, platelet-derived growth factor

Differential expression of platelet-derived growth factor receptor-ß in an aging model of wound repair. (Brucker et al) 1996;4:219-23

Regeneration

Dermal regeneration in native non-cross-linked collagen sponges with different extracellular matrix molecules (de Vries et al). 1994;2:37-47

Specific effects of glycosaminoglycans in an analog of extracellular matrix that delays wound contraction and induces regeneration (Shafritz et al). 1994;2:270-6

Mammalian wound repair environment does not permit skeletal muscle regeneration (Sicard et al). 1997;5:39-46

Regulations

Regulatory concerns in the development of topical recombinant ophthalmic and cutaneous wound healing biologics (Stromberg et al). 1994;2:155-64

Reperfusion<

Microanalyses of enzymes and metabolites inischemia/reperfusion-induced partial-thickness skin wounds (Im et al). 1993;1:253-8

Acidic fibroblast growth factor reduces renal morphologic and functional indicators of injury caused by ischemia and reperfusion (Fu et al). 1996;4:297-303

Ischemia and reperfusion reduce the endogenous basic fibroblast growth factor in rat skeletal muscles: an immunohistochemical study (Fu et al). 1996;4:381-5

Revascularization

Capillary morphogenesis during healing of full-thickness skin grafts: an ultrastructural study (Goretsky et al). 1995;3:213-20

RNA, messenger

Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b (Ghahary et al). 1993;1:166-74

Regulation of collagen synthesis and messenger RNA levels in normal and hypertrophic scar fibroblasts in vitro by interferonh)%0*0*0* alfa-2b (Tredget et al). 1993;1:156-65

Interferons gamma and alpha-2b differentially regulate the expression of collagenase and tissue inhibitor of metalloproteinase-1 messenger RNA in human hypertrophic and normal dermal fibroblasts (Ghahary et al). 1995;3:176-84

Differential expression of platelet-derived growth factor receptor-( in an aging model of wound repair (Brucker et al). 1996;4:219-23

Expression of bone morphogenetic protein-4 mRNA during the process of bone formation in embryogenesis and fracture repair (Nakase et al). 1996;4:82-6 (Symposium)

Wound fluids from saline solution- and Saphylococcus aureus peptidoglycan-inoculated sponges induce expression of matrix metalloproteinase 13 messenger ribonucleic acid by cultured rat fibroblasts (Liu et al). 1997;5:349-54

S

Sarcoids

Effect of growth factors on the characteristics of cells associate with equine wound healing and sarcoid formation (Cochrane et al). 1996;4:58-65

Scar; see Cicatrix

Scatter factor

Increased gene expression of scatter factor-hepatocyte growth factor and basic fibroblast growth factor in granulation tissue in the rat (Steenfos et al). 1993;1:231-5

Sensitivity and specificity

Interobserver agreement sensitivity, and specificity of a "healed" chronic wound (Margolis et al). 1996;4:335-8

Sickle cell anemia; see Anemia, sickle cell

Skeletal muscle

Mammalian wound repair environment does not permit skeletal muscle regeneration (Sicard et al). 1997;5:39-46

Skin

Dermal substitutes for full-thickness wounds in a one-stage grafting model (de Vries et al). 1993;1:244-52

Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b (Ghahary et al). 1993;1:166-74

Microanalyses of enzymes and metabolites in ischemia/reperfusion-induced partial-thickness skin wounds (Im et al). 1993;1:253-8

Exogenous transforming growth factor-ß2 enhances connective tissue formation in transforming growth factor-ß1-deficient, healing-impaired dermal wounds in mice (Ksander et al). 1993;1:137-48

Mechanical analysis of the effects of bacteria and aprotinin on skin wound healing in adult guinea pigs (Stadelmann et al).h)&0*0*0* 1993;1:187-93

Hyaluronan, heterogeneity, and healing: the effects of ultrapure hyaluronan of defined molecular size on the repair of full-thickness pig skin wounds (Arnold et al). 1995;3:299-310

In vitro reconstituted skin as a tool for biology, pharmacology and therapy: a review (Eckes et al). 1995;3:248-57 (Perspective)

Increased specific binding of insulin-like growth factor-I in healing cutaneous wounds (Hakim et al). 1995;3:492-9

Healing of full-thickness wounds treated with lyophilized cultured keratinocyte cell lysate in genetically diabetic mice (Roseeuw et al). 1995;3:500-5

Exchange and the mechanical properties of the skin: oncotic and hydrostatic forces control by blood supply and lymphatic drainage (Ryan). 1995;3:258-64 (Clinical issues)

Effects of insulin-like growth factor-I and insulin-like growth factor binding protein-I on wound healing in a dermal ulcer model (Zhao et al). 1995;3:316-21

Alterations of angiotensin II receptor levels in full-thickness excisional wounds in rat skin (Abiko et al). 1996;4:363-7

Differential expression of platelet-derived growth factor receptors in porcine fibroblasts cultured from skin and granulation tissue (Ågren et al). 1996;4:288-96

Skin changes with aging and disease (Jacobson and Flowers). 1996;4:311-5 (Perspective)

Growth hormone increases the biomechanical strength and collagen deposition rate during the early phase of skin wound healing (J$rgensen and Oxlund). 1996;4:40-7

Mesenchymal-epithelial interactions regulate gene expression of type VII collagen and kalinin in keratinocytes and dermal-epidermal junction formation in a skin equivalent model (Sahuc et al). 1996;4:93-102 (Symposium)

Differential effects of oxygen on human dermal fibroblasts: acute versus chronic hypoxia (Siddiqui et al). 1996;4:211-8

Tissue expression of transforming growth factor-ß1 and transforming growth factor-alpha during wound healing in human skin explants (see Kratz et al). 1997;5:222-8

Growth hormone but not insulin-like growth factor-I improves wound strength in pigs (Robertson et al). 1997;5:168-74

Acceleration of dermal tissue repair by angiotensin II (Rodgers et al). 1997;5:175-83

Skin substitutes

Surface electrical capacitance as an index of epidermal barrier properties of composite skin substitutes and skin autografts (Groetsky et al). 1995;3:419-25

Effective management of microbial contamination in cultured skin subtitutes after grafting to athymic mice (Boyce et al). 1997;5:191-7

Epidermal lipid metabolism of cultured skin substitutes during healing of full-thickness wounds in athymic mice (Vi_anová et al). 1997;5:327-36

Skin transplantation

Capillary morphogenesis during healing of full-thickness skinh)'0*0*0* grafts: an ultrastructural study (Goretsky et al). 1995;3:213-20

Surface electrical capacitance as an index of epidermal barrier properties of composite skin substitutes and skin autografts (Groetsky et al). 1995;3:419-25

Smooth muscle; see Muscle, smooth

Smooth muscle actin

Alpha-smooth muscle actin expression in rat and mouse mesenteric wounds after Transforming Growth Faactor-ß1 treatment (Ghassemifar et al). 1997;5:339-48

Somatomedins

Synergistic actions of platelet-derived growth factor and the insulin-like growth factors in vivo: enhancement of tissue repair in genetically diabetic mice (Greenhalgh et al). 1993;1:69-81

Spinal cord injuries

Effect of electrical stimulation waveform on healing of ulcers in human being with spinal cord injury (Baker et al). 1996;4:21-8

Stapylococcus aureus

Mild hypothermia during halothane-induced anesthesia decreases resistance to Staphylococcus aureus dermal infection in guinea pigs (Sheffield et al). 1994;2:48-56

Wound healing I: accelerating effects of nonviable Staphylococcus aureus, its cell wall, and cell wall peptidoglycan (Levenson et al). 1996;4:461-9

Molecular mechanism underlying wound healing acceleration by Staphylococcus aureuspeptidoglycan (Liu et al). 1996;4:470-6

Single local instillation of nonviable staphylococcus aureus or its peptidoglycan ameliorates glucocorticoid-induced impaired wound healing (see Chang et al). 1997;5:184-190

Staphylococcus aureus peptidoglycan ameliorates cyclophosphamide-induced impairment of wound healing (Imegwu et al). 1997;5:364-72

Wound fluids from saline solution- and Staphylococcus aureus peptidoglycan-inoculated sponges induce expression of matrix metalloproteinase 13 messenger ribonucleic acid by cultured rat fibroblasts (Liu et al). 1997;5:349-54

Stem cells

Tissue restoration: approaches and prospects (Stocum). 1996;4:3-15 (Perspective)

Streptozotocin-induced diabetes; seeDiabetes mellitus, experimental

Subglottic stenosis

Canine subglottic stenosis as a model for excessive fibrosis: a pilot histologic and immunohistochemical analysis (Charous et al). 1996;4:444-53

h)(0*0*0*Ԍ

Surface electrical capacitance

Surface electrical capacitance as an index of epidermal barrier properties of composite skin substitutes and skin autografts (Goretsky et al). 1995;3:419-25

Surgical gloves; see Gloves, surgical

Surgical flaps

Covering by a flap induces apoptosis of granulation tissue myofibroblasts and vascular cells (Garbin et al). 1996;4:244-51

T

Technical note

Rabbit cornea assay of angiogenesis: methodology and evaluation (Phillips and Knighton). 1995,3:533-9

Tenascin

Gene expression of tenascin is altered in normal scars and keloids (Sible et al). 1995;3:37-48

Tendons

Progression of cellular repopulation and collagen synthesis in fresh-frozen allograft tendons (Nakamura et al). 1996;4:87-92 (Symposium)

Rate of tendon gap closure in an in vitro collagen gel matrix. (Dombi et al). 1997;5:62-68

Tensile strength

Low-energy helium-neon laser irradiation and the tensile strength of incisional wounds in the rat (Broadley et al). 1995;3:512-7

Thermal burns

Comparisons of wound healing among excisional, laser-related, and standard thermal burns in porcine wounds of equal depth (Schaffer et al). 1997;5:52-61

Thermoregulation; see Body temperature regulation

Tissue regeneration

Getting to mammalian wound repair and amphibian limb regeneration: a mechanistic link in the early events (Gross). 1996;4:190-202 (Award recipient address)

Tissue restoration: approaches and prospects (Stocum). 1996;4:3-15 (Perspective)

Extracellular matrix protein turnover during salamander limb regeneration (Tassava et al). 1996;4:75-81 (Symposium)

Tracheostomal healing

Early tracheostomal healing in rabbits with use of various trachael incisions (Whitley et al). 1997;5:321-6

Transcortin

Effect of burn injury on corticosteroid-binding globulin levelsh))0*0*0* in plasma and wound fluid (Garrel et al). 1993;1:10-4

Transcutaneous oxygen monitoring; see Blood gas monitoring, transcutaneous

Transforming growth factor-alpha

Cellular distribution of epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor in fascia and peritoneum during healing in the rat: an autoradiographic and immunohistochemical study (Chegini et al). 1993;1:28-40

Correlation of transforming growth factor-alpha and epidermal growth factor receptor with proliferating cell nuclear antigen in human burn wounds (Wenczak and Nanney). 1993;1:219-30

Tissue expression of transforming growth factor-ß1 and transforming growth factor-alpha during wound healing in human skin explants (Kratz et al). 1997;5:222-8

Transforming growth factor-ß

Transforming growth factor-ß enhances connective tissue repair in perforated rat mesentery but not peritoneal macrophage chemotaxis (Franzén and Schultz). 1993;1:149-55

Exogenous transforming growth factor-ß2 enhances connective tissue formation in transforming growth factor-ß1-deficient, healing-impaired dermal wounds in mice (Ksander et al). 1993;1:137-48

Role of transforming growth factor-ß1 and epidermal growth factor in the wound healing process: an in vivo biomechanical evaluation (Perry et al). 1993;1:41-6

Autocrine transforming growth factor-ß1 activity and glycosaminoglycan synthesis by human cutaneous scar fibroblasts (Messadi et al). 1994;2:284-91

Wound healing in the fetus: possible role for inflammatory macrophages and transforming growth factor-ß isoforms (Longaker et al). 1994;2:104-12

Wound healing in the transforming growth factor-ß1-deficient mouse (Brown et al). 1995;3:25-36

Mechanisms of TGF-ß action in connective tissue repair of rat mesenteric wounds (Franzn et al). 1995;3:322-9

The role of transforming growth factor-ß in the conversion from "scarless" healing to healing with scar formation (Houghton et al). 1995;3:229-36

Spatial and temporal expression of transforming growth factor-ß isoforms during ovine excisional and incisional wound repair (McMullen et al). 1995;3:141-56

Differential response to transforming growth factors-ß1 and ß2: connective tissue deposition in animal models (Ogawa et al). 1995;3:485-91

Acceleration of wound healing in aged rats by topical application of transforming growth factor-ß1 (Puolakkainen et al). 1995;3:330-9

Transforming growth factor-ß: activity and efficacy in animal models of wound healing (Roberts). 1995;3:408-18 (Perspective)

Safety and effect of transforming growth factor-ß2 for treatment of venous stasis ulcers (Robson et al). 1995;3:157-67

h)*0*0*0*Ԍ

Transforming growth factor-ß1 reduces expansion of open wounds in the fetal rabbit (Alaish et al). 1996;4:477-81

Inhibition of wound closure by transforming growth factor-ß and dexamethasone in a fetal mouse limb organ culture model (Ehrlich et al). 1996;4:482-8

Negatively charged beads and transforming growth factor-ß1 stimulate bone repair in rabbits (Lyle et al) 1996;4:368-73

Effects of transforming growth factor-ß1 on extracellular matrix gene expression by human fibroblasts from a laryngeal stenotic lesion (Macauley et al). 1996;4:269-77

Modulation of alpha-smooth muscle actin expression in fibroblasts by transforming growth factor-ß isoforms: an in vivo and in vitro study (Serini and Gabbiani). 1996;4:278-87

Reversal of the wound healing deficit in diabetic rats by combined basic fibroblast growth factor and transforming growth factor-ß1 therapy (Davidson et al). 1997;5:77-88

Alpha-smooth muscle actin expression in rat and mouse mesenteric wounds after Tranforming Growth Factor-&szing;1 treatment (Ghassemifar et al). 1997;5:339-48

Tissue expression of transforming growth factor-ß1 and transforming growth factor-alpha during wound healing in human skin explants (Kratz et al). 1997;5:222-8

Abrogation of the fibrotic effect of transforming growth factor-ß in dermal healing (Parrelli et al). 1997;5:136-140

Expression of endogenous transforming growth factor-ß and its type I and type II receptors in rat burn wounds (Wei et al). 1997;5:229-34

Transforming growth factor ß receptor

Expression of endogenous transforming growth factor-ß and its type I and type II receptors in rat burn wounds (Wei et al). 1997;5:229-34

Transforming growth factor type e

Transforming growth factor type e is a novel mediator of wound repair (Carter and Halper). 1996;4:259-68

Transglutaminase; see Protein-glutamine gamma-glutamyltransferase

Triple-layer treatment; see Bandages

Tumor necrosis factor

Expression of interleukin-6 and tumor necrosis factor in peritoneal monomuyclear cells after gastrectomy (Fujita et al). 1995;3:168-75

U

Ulcers, Dermal

Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-L-histidyl-L-lysine copper (Mulder et al). 1994;2:259-69

Safety and effect of topical recombinant human interleukin-1( in the management of pressure sores (Robson et al).h)+0*0*0* 1994;2:177-81

Localization of platelet-derived growth factor receptor subunit expression in chronic venous leg ulcers (Peus et al). 1995;3:265-72

Safety and effect of transforming growth factor-ß2 for treatment of venous stasis ulcers (Robson et al). 1995;3:156-67

Involvement of proteolytic enzymes-plasminogen activators and matrix metalloproteinases-- in the pathophysiology of pressure ulcers (Rogers et al). 1995;3:273-83

Effects of insulin-like growth factor-I and insulin-like growth factor binding protein-1 on wound healing in a dermal ulcer model (Zhao et al). 1995;3:316-21

Effect of electrical stimulation waveform on healing of ulcers in human being with spinal cord injury (Baker et al). 1996;4:21-8

Pressure ulcers in older persons: a preventive approach (Conlin Shaw). 1996;4:316-20 (Perspective)

Histochemical analysis of growth factor, fibronectin, and iron content of sickle cell leg ulcers (Francillon et al). 1996;4:240-3

Recurrence rate of diabetic neurotrophic foot ulcers healed using topical application of growth factors released from platelets (Steed et al). 1996;4:230-3

Biochemical analysis of wound fluid from nonhealing and healing chronic leg ulcers (Trengove et al). 1996;4:234-9

Long-term results of aggressive management of diabetic foot ulcers suggest significant cost effectiveness (Cianci and Hunt). 1997;5:141-6

DD>Low-frequency ultrasound treatment of chronic venous ulcers (Weichenthal et al). 1997;5:18-22

Ultrasound

Low-frequency ultrasound treatment of chronic venous ulcers (Weichenthal et al). 1997;5:18-22

Ultrastructure

Ultrastructural analysis of fetal rabbit wounds (Mast et al). 1997;5:243-8

Ultraviolet rays

Effect of ultraviolet radiation-induced inflammation on epidermal wound healing (Kaiser et al). 1995;3:311-5

V

Vascular cells; see Blood vessels, cytology

Venous ulcer

Analysis of therapy-resistant venous leg ulcers: Can triple-layer treatment initiate healing? (Bjellerup et al). 1993;1:54-62

Localization of platelet-derived growth factor receptor subunit expression in chronic venous leg ulcers (Peus et al).1995;3:265-72

Safety and effect of transforming growth factor-ß2 for treatment of venous stasis ulcers (Robson et al). 1995;3:156-67

h),0*0*0*Ԍ

Low-frequency ultrasound treatment of chronic venous ulcers (Weichenthal et al). 1997;5:18-22

Vibriolysin

Effect of vibriolysin, an enzymatic debriding agent, on healing of partial-thickness burn wounds (Nanney et al); (Greenhalgh - Editorial comment). 1995;3:442-8, 540-1

Vietnam

In vitro studies on the antioxidant and growth stimulatory activities of a polyphenolic extract from cudrania cochinchinensis used in the treatment of wounds in Vietnam (Van Hien et al). 1997;5:159-67

Vitamin C

Differential regulation of collagen gene expression in granulation tissue and nonrepair connective tissues in vitamin C-deficient guinea pigs (Kipp et al). 1995;3:192-203

W



Wound closure

Mouse models to study wound closure and topical treatment of infected wounds in healingimpaired and normal hosts (Holder et al). 1997;5:198-204

Wound contraction

In vitro and in vivo analysis of the inability of fetal rabbit wounds to contract (Krummel et al). 1993;1:15-21

Suppression of in vitro proliferative scar fibroblast contraction by interferon alfa-2b (Sahara et al). 1993;1:22-7

Specific effects of glycosaminoglycans in an analog of extracellular matrix that delays wound contraction and induces regeneration (Shafritz et al). 1994;2:270-6

Actin fiber orientation in connective tissue contraction: a quantitative study with the perforated rat mesentery model (Franzén et al). 1996;4:454-60

Fetal wound healing; an overview (Olutoye and Cohen). 1996;4;66-74 (Symposium)

Regulation of wound healing from a connective tissue perspective (Ehrlich and Krummel). 1996;4:203-10 (Perspective)

Wound contraction and scar synthesis during development of the amphibian Rana catesbeiana (Yannas et al). 1996;4:29-39

Wound debridement

Effect of vibriolysin, an enzymatic debriding agent, on healing of partial-thickness burn wounds (Nanney et al); (Greenhalgh - Editorial comment). 1995;3:442-8; 540-1

Removal of necrotic tissue with ananain-based enzyme debriding preparation (Skrabut et al). 1996;4:433-43

Wound fluid

Inhibition of cell proliferation by chronic wound fluid (Bucalo et al). 1993;1:181-6

Effect of burn injury on corticosteroid-binding globulin levels in plasma and wound fluid (Garrel et al). 1993;1:10-4

h)-0*0*0*Ԍ

Detection of the actin scavenger system in burn wound fluid (Grinnell et al). 1993;1:236-43

Effects of cytokines in burn blister fluids on fibroblast proliferation and their inhibition with the use of neutralizing antibodies (Inoue et al). 1996;4:426-32

Biochemical analysis of wound fluid from nonhealing and healing chronic leg ulcers (Trengove et al). 1996;4:234-9

Wound fluids from saline solution- and Staphylococcus aureus peptidoglycan-inoculated sponges induce expression of matrix metalloproteinase 13 messenger ribonucleic acid by cultured rat fibroblasts (Liu et al). 1997;5:349-54

Wound healing deficit

Reversal of the wound healing deficit in diabetic rats by combined basic fibroblast growth factor and transforming growth factor-ß1 therapy (Davidson et al). 1997;5:77-88

Wound, peritoneal; seePeritoneal wounds

Wound, rabbit; see Rabbit repair

Wound repair environment

Mammalian wound repair environment does not permit skeletal muscle regeneration (Sicard et al). 1997;5:39-46

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